Computing for Comparative Microbial Genomics: Bioinformatics for Microbiologists (Computational Biology)
by David W. Ussery, Trudy M. Wassenaar, Stefano Borini
Computing for Comparative Microbial Genomics: Bioinformatics for Microbiologists (Computational Biology)
By David W. Ussery, Trudy M. Wassenaar, Stefano Borini
Publisher: Springer
Number Of Pages: 274
Publication Date: 2008-12-11
ISBN-10 / ASIN: 1848002548
ISBN-13 / EAN: 9781848002548
Binding: Hardcover
The major difficulty many microbiologists face is simply that of too
much information. As a result of sequencing technologies becoming so
economical, there is a very real and pressing need for high-throughput
computational methods to compare hundreds and thousands of bacterial
genomes.
This accessible text/reference provides a coherent set of tools and
a methodological framework for comparing raw DNA sequences and fully
annotated genome sequences, then using these to build up and test
models about groups of interacting organisms within an environment or
ecological niche. Easy-to-follow, this introductory textbook is built
around teaching computational / bioinformatics methods for comparison
of microbial genomes, and includes detailed examples of how to compare
them at the level of DNA, RNA, and protein, in terms of structural and
functional analysis.
Topics and Features:
鈥?Contains five introductory chapters each representing a specific
scientific field, to bring all readers up to the same basic level
鈥?Familiarizes readers with genome sequences, RNA sequences (transcriptomics), proteomics and regulation of gene expression
鈥?Describes basic methods to compare genomes and visualize the results for easy interpretation
鈥?Discusses microbial communities, providing a framework for
analysing and comparing individual genomes or raw DNA derived from
complete ecosystems
鈥?Introduces various atlases, building up to the Genome Atlas
鈥?Offers numerous helpful examples throughout
鈥?Focuses on the use and interpretation of publicly available Web tools
鈥?Provides supplemental resources, such as Web links, at http://comparativemicrobial.com
Developed from a set of lectures for a course in Comparative
Microbial Genomics taught since 2001, this wide-ranging foundational
textbook is aimed at advanced undergraduate and graduate students in
Bioinformatics and Microbiology. The authors are from diverse
backgrounds complementing the interdisciplinary nature of the topic and
consequently have developed a common scientific language. Readers will
find this text an invaluable reference for computational and
bioinformatics tools.
http://rapidshare.com/files/174598277/0please.rar
by David W. Ussery, Trudy M. Wassenaar, Stefano Borini
Computing for Comparative Microbial Genomics: Bioinformatics for Microbiologists (Computational Biology)
By David W. Ussery, Trudy M. Wassenaar, Stefano Borini
Publisher: Springer
Number Of Pages: 274
Publication Date: 2008-12-11
ISBN-10 / ASIN: 1848002548
ISBN-13 / EAN: 9781848002548
Binding: Hardcover
The major difficulty many microbiologists face is simply that of too
much information. As a result of sequencing technologies becoming so
economical, there is a very real and pressing need for high-throughput
computational methods to compare hundreds and thousands of bacterial
genomes.
This accessible text/reference provides a coherent set of tools and
a methodological framework for comparing raw DNA sequences and fully
annotated genome sequences, then using these to build up and test
models about groups of interacting organisms within an environment or
ecological niche. Easy-to-follow, this introductory textbook is built
around teaching computational / bioinformatics methods for comparison
of microbial genomes, and includes detailed examples of how to compare
them at the level of DNA, RNA, and protein, in terms of structural and
functional analysis.
Topics and Features:
鈥?Contains five introductory chapters each representing a specific
scientific field, to bring all readers up to the same basic level
鈥?Familiarizes readers with genome sequences, RNA sequences (transcriptomics), proteomics and regulation of gene expression
鈥?Describes basic methods to compare genomes and visualize the results for easy interpretation
鈥?Discusses microbial communities, providing a framework for
analysing and comparing individual genomes or raw DNA derived from
complete ecosystems
鈥?Introduces various atlases, building up to the Genome Atlas
鈥?Offers numerous helpful examples throughout
鈥?Focuses on the use and interpretation of publicly available Web tools
鈥?Provides supplemental resources, such as Web links, at http://comparativemicrobial.com
Developed from a set of lectures for a course in Comparative
Microbial Genomics taught since 2001, this wide-ranging foundational
textbook is aimed at advanced undergraduate and graduate students in
Bioinformatics and Microbiology. The authors are from diverse
backgrounds complementing the interdisciplinary nature of the topic and
consequently have developed a common scientific language. Readers will
find this text an invaluable reference for computational and
bioinformatics tools.
http://rapidshare.com/files/174598277/0please.rar