Microbial Gene Essentiality: Protocols and Bioinformatics (Methods in Molecular Biology)
Microbial Gene Essentiality: Protocols and Bioinformatics (Methods in Molecular Biology)
By Andrei L. Osterman, Svetlana Gerdes
Publisher: Humana Press
Number Of Pages: 400
Publication Date: 2008-02-04
ISBN-10 / ASIN: 1588293785
ISBN-13 / EAN: 9781588293787
Binding: Hardcover
Microbial Gene Essentiality: Protocols and Bioinformatics contains a
comprehensive collection of experimental and computational strategies
and techniques for microbial genome-scale essentiality studies,
developed and presented by the leading groups in the field. In addition
to wet-lab protocols, the book describes (i) statistical methods
essential for planning successful large-scale essentiality screens, as
well for data evaluation and analysis; (ii) in-silico prediction of
gene essentiality using genome-scale reconstructed metabolic models;
and (iii) data integration and comparative analysis in the context of
genomic databases. This volume provides researchers with a first-stop
guide for choosing the most appropriate strategy for planned
essentiality studies. Experimental and computational aspects are
equally important in genome-scale gene essentiality analysis, as in all
other genomic technologies, and Microbial Gene Essentiality: Protocols
and Bioinformatics reflects both of these aspects. All protocols follow
the successful Methods in Molecular Biology series format, each
offering an introduction outlining the principles behind the
techniques, step-by-step instructions, lists of the necessary equipment
and reagents, and tips on troubleshooting and avoiding pitfalls, and
are intended for both novice and expert scientists.
http://rapidshare.com/files/96120434/416-MMB.rar
Microbial Gene Essentiality: Protocols and Bioinformatics (Methods in Molecular Biology)
By Andrei L. Osterman, Svetlana Gerdes
Publisher: Humana Press
Number Of Pages: 400
Publication Date: 2008-02-04
ISBN-10 / ASIN: 1588293785
ISBN-13 / EAN: 9781588293787
Binding: Hardcover
Microbial Gene Essentiality: Protocols and Bioinformatics contains a
comprehensive collection of experimental and computational strategies
and techniques for microbial genome-scale essentiality studies,
developed and presented by the leading groups in the field. In addition
to wet-lab protocols, the book describes (i) statistical methods
essential for planning successful large-scale essentiality screens, as
well for data evaluation and analysis; (ii) in-silico prediction of
gene essentiality using genome-scale reconstructed metabolic models;
and (iii) data integration and comparative analysis in the context of
genomic databases. This volume provides researchers with a first-stop
guide for choosing the most appropriate strategy for planned
essentiality studies. Experimental and computational aspects are
equally important in genome-scale gene essentiality analysis, as in all
other genomic technologies, and Microbial Gene Essentiality: Protocols
and Bioinformatics reflects both of these aspects. All protocols follow
the successful Methods in Molecular Biology series format, each
offering an introduction outlining the principles behind the
techniques, step-by-step instructions, lists of the necessary equipment
and reagents, and tips on troubleshooting and avoiding pitfalls, and
are intended for both novice and expert scientists.
http://rapidshare.com/files/96120434/416-MMB.rar
