Bioinformatics for Systems Biology
by: Stephen Krawetz
Bioinformatics for Systems Biology
By Stephen Krawetz
Publisher: Humana Press
Number Of Pages: 740
Publication Date: 2009-02-17
ISBN-10 / ASIN: 1934115029
ISBN-13 / EAN: 9781934115022
Product Description:
The biological sciences are now in the midst of a true life sciences
revolution akin to what physics experienced just after the turn of the
last century. We are now in a phase of unparalleled growth that is
reflected by the amount of data generated from each experiment. At the
time of this writing, the rate of data acquisition was approaching 2
terabytes over the course of 5 days with first pass analysis proceeding
over the following 2-3 week period. This fundamental shift has provided
unprecedented opportunities that for the first time afford us the
ability, i.e., means, breadth, and depth of data, to truly address
human biology at the systems level. This wealth of information from
seemingly disparate datasets and its integration is being realized
through bioinformatics. It is with this philosophy that the text
"Bioinformatics for Systems Biology" was born. This revolution has
spawned true personalized medicine that encompasses diagnostics and
treatment through to cure. For the physical and computer scientist,
this text provides an introduction to the basic biological principles
governing a cell. This quickly moves from the fundamentals to exploring
the underlying genetic processes. While providing a rudimentary and
necessary overview for the life scientist, the physical and computer
scientist will be apprised of various nuances within the field
reflecting the reality of 'wet-bench' science. For those in the life
sciences, it is rapidly becoming appreciated that we are progressing
from examining our favorite 'pet' gene to the system. Statistics is now
an essential component to understand the vast datasets and this is
emphasized throughout the text. The majority of the text is devoted to
the common ground that these groups share. It provides rich examples of
tools, databases, and strategies to mine the databases to reveal novel
insights. A host of examples of parsing the data into a series of
overlays that use various presentation systems are reviewed. The goal
is to provide a representation most comfortable to the user to enable
the user to thoroughly explore the data. The text concludes with
examples of how the systems information is used to inform personalized
medicine in a true 'bench to bedside' manner. "Bioinformatics for
Systems Biology" bridges and unifies many disciplines. It presents the
life scientist, computational biologist, and mathematician with a
common framework. Only by linking the groups together may the true life
sciences revolution move forward in the mostly uncharted and emerging
field of Systems Biology.
http://ugotfile.com/file/322233/1934115029.rar
http://www.fileflyer.com/view/EkC6PCD
by: Stephen Krawetz
Bioinformatics for Systems Biology
By Stephen Krawetz
Publisher: Humana Press
Number Of Pages: 740
Publication Date: 2009-02-17
ISBN-10 / ASIN: 1934115029
ISBN-13 / EAN: 9781934115022
Product Description:
The biological sciences are now in the midst of a true life sciences
revolution akin to what physics experienced just after the turn of the
last century. We are now in a phase of unparalleled growth that is
reflected by the amount of data generated from each experiment. At the
time of this writing, the rate of data acquisition was approaching 2
terabytes over the course of 5 days with first pass analysis proceeding
over the following 2-3 week period. This fundamental shift has provided
unprecedented opportunities that for the first time afford us the
ability, i.e., means, breadth, and depth of data, to truly address
human biology at the systems level. This wealth of information from
seemingly disparate datasets and its integration is being realized
through bioinformatics. It is with this philosophy that the text
"Bioinformatics for Systems Biology" was born. This revolution has
spawned true personalized medicine that encompasses diagnostics and
treatment through to cure. For the physical and computer scientist,
this text provides an introduction to the basic biological principles
governing a cell. This quickly moves from the fundamentals to exploring
the underlying genetic processes. While providing a rudimentary and
necessary overview for the life scientist, the physical and computer
scientist will be apprised of various nuances within the field
reflecting the reality of 'wet-bench' science. For those in the life
sciences, it is rapidly becoming appreciated that we are progressing
from examining our favorite 'pet' gene to the system. Statistics is now
an essential component to understand the vast datasets and this is
emphasized throughout the text. The majority of the text is devoted to
the common ground that these groups share. It provides rich examples of
tools, databases, and strategies to mine the databases to reveal novel
insights. A host of examples of parsing the data into a series of
overlays that use various presentation systems are reviewed. The goal
is to provide a representation most comfortable to the user to enable
the user to thoroughly explore the data. The text concludes with
examples of how the systems information is used to inform personalized
medicine in a true 'bench to bedside' manner. "Bioinformatics for
Systems Biology" bridges and unifies many disciplines. It presents the
life scientist, computational biologist, and mathematician with a
common framework. Only by linking the groups together may the true life
sciences revolution move forward in the mostly uncharted and emerging
field of Systems Biology.
http://ugotfile.com/file/322233/1934115029.rar
http://www.fileflyer.com/view/EkC6PCD
